Institute for Pulmonay Diseases,
THE ROLE OF THE VIRUS RESPIRATORY
INFECTIONS IN THE
Miloš FILIPOVIĆ1, Boiis ĐINDIĆ2, Svetlana PLJASKIĆ-KAMENOV3 i Olivera DUNJIĆ2
Institute for Pulmonay Diseases1,
Institute for Pathologic Physiology of the Faculty of Medicine2
Medical Center, Niš3
The virus infections of the respiratory pathways represent an important cause of the emergence of the symptoms of the puffing (wheezing) in the lungs of the patients of all age groups. In the patients suffering from asthma the virus respiratory infections are the main causes of asthmatic exarcebations. In 80 to 85 % of the school children and in 50 % of the adult asthmatics, the exarcebations are caused by the respiratory virus infection while the most frequent cause is the rhinovirus. It is believed that in the pathogenesis of the virus-induced asthmatic exarcebations the following mechanisms are involved: the damage of the epithelium, the inflammation increase in the respiratory pathways, the disturbance of the small respiratory pathways' geometry, the disturbance of the nerve controlling mechanisms and the disturbance of the IgE synthesis regulation.