Acta Medica Medianae
CYSTINURIA - A TEN-YEAR FOLLOW-UP OF THE PATIENTS
Emilija GOLUBOVIĆ, Predrag MILJKOVIĆ, Anđelka SLAVKOVIĆ and Saša ŽIVIĆ
Children Internal Clinic of the Clinic Center, Niš
In the period from 1991 to 2001 there were four patients followed up who suffered from cystinuria and cystine calcinosis. The therapy consisting of the cystine dilution in the urine by a great taking-in of liquids and the urine alkalization was combined with alphamercaptopropione glycine and captoprile that bind cystine as well as a respective diet. Alphamercaptopropione glycine leads to the reduction of the already-formed calculus and their easier treatment in the case of a possible need for extracorporeal lithotripsy (ESWEL). During the ten-year follow-up of a small series of patients there were no complications related to the medicament treatment.
Key words: Cystinuria, therapy, child age