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Acta Medica Medianae
Vol. 41
No 5, 2002
UDK 61
YU ISSN 0365-4478


Miodrag Radović
Gynecological-0bstetric Clinic in Nis






Miodrag Radović, Milena Veljković, Zoran Pop-Trajković, Miljan Krstić, Snežana Jančić and Vuka Katić


Gynecological-0bstetric Clinic and

the Institute for Pathology and Pathological Anatomy of the Clinic Center, Nis


The cytological diagnostic method has been more and more used in medical practice. Thanks to the Greek scientist Papanicolaou and his reports (1928), a new preventive struggle with the most frequent carcinoma of the genital tract, that is, the PVU carcinoma has begun. In the last few decades the number of cytological methods has increased as well while impressive results have been achieved upon the preparations obtained by exfoliative, brushing and lavage methods as well as the aspiration techniques with a thin and thicker needled.

For the above-stated reasons as well as due to scant literature in our country, the aim of this paper is to present a survey of the history, examination of advantages and drawbacks of various cytological methods as well as of a still widely used Pap-classification in medical practice. The importance of the Bethesda-classification is also pointed out.

Because of possible artifacts and errors in interpreting the obtained cytological results when the precancerous and malign lesions of the regenerative epithelium -such as the well-known squamous epithelium PVU - special attention is paid to cytological and mclear characteristics of the taken sample.


Key words: Cytopathology, methods, classification, cytological characteristics