Acta Medica Medianae
THE ROLE OF CIRCULATING IMMUNOCOMPLEXES
IN THE SCLERITIS PATHOGENESIS
Jasmina Đorđević-Jocić and Gordana Zlatanović
Ophthalmologic Clinic of the Clinic
Scleritis is an inflammation of deep layers of the white that can have an unfavorable course. It can appear on its own or coupled with the system diseases of the connective tissue. It i.s believed that in its pathogenesis an important role is played by vasculitis of small blood vessels at whose basi.s the III type of hypersensitive reaction is laying (oversensitivity mediated by the immunocomplexes).
Three groups ofpatients were subjected to
a prospective study namely the 1st group compnsing 15
patients with scleritis of unknovvn etiology the 2nd group
comprising 15 patients who had scleritis coupled with the system
diseases and the 3rd group of 15 healthy patients. In our
work we followed immunological parameters, namely, C3
complement component and the level ofcirculating immunocomplexes -CIC in
the serum; we compared them with the clinic parameters (number of
recidivism and recovery time).
Key words: Scleritis, recidivism, recovery time, complement, circulating immunocomplexes