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Acta Medica Medianae
Vol. 42
Number 4, Oktobar, 2003
UDK 61
YU ISSN 0365-4478


Goran Damnjanovic
Interno odcljenje Vojne bolnice
Brace Tasković bb, 18000 Niš, Srbija i Crna Gora
Tel.: 018/ 508-834, e-mail: GORAN7328@bankerinter.net




Goran Damnjanovic*, Boris Đinđic**, Vekoslav Mitrovic*, Dragan Jovovic*, Slobodanka Veličković* i Ruzica Janković***


Interno odeljenje Vojne bolnice u Nišu*
Institut za patološku fiziologiju Medicinskog fakulteta u Nišu**
Klinika za kardiologiju Kliničkog centra u Nišu***

 The aim of this study was to examine echocardiographic and ergometric disorders in noninsulin dependent diabetics with myocardial infarction and their correlation with appearing of left ventricular diastolic dysfunction.
We examined 80 patients with myocardial infarction (MI) treated in Military Hospital in Nis. They were divided into two groups: diabetics and non-diabetics. Doppler echocardiography was used for evaluating left ventricular diastolic function, and ergometric parameters were obtained by bicycle ergometer "Quinton" - Bruce protocol. Diastolic blood pressure and heart rate were higher in diabetics. Double product and power (68.7513.5 and 5014.97W) were lower in diabetics. They also had frequent appearances of ST depression, dyspnea, palpitation, and rhythm disturbances in rest and after ergotest. Fatigue and pain were more prominent symptoms in non-diabetics. The Doppler mitral E wave was similar between these groups and the A wave was increased in diabetics (0.51 0.05 vs. 0.480.09, p<0.01). E/A ratio was significantly decreased in diabetics as a sign of worst diastolic dysfunction (1.140.09 vs. 1.260.17; p<0.01). Acta Medica Medianae 2003; 42

Key words: diastolic dysfunction, diabetes mellitus, ergometry, echocardiography