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Acta Medica Medianae
Vol. 46, No 1, January, 2007
UDK 61
YU ISSN 0365-4478

Correspondence to:
Mirjana Bakić

18000 Niš, SrbijaText Box: www.medfak.ni.ac.yu/amm

 Tel.: 018/253-666

E-mail: nbakic@eunet.yu



Copyright 2007 by Faculty  of Medicine, University of Nis



Mirjana Bakic



 Atherosclerosis is a chronic progressive disease, which develops from the moment of birth. Lipid deposit in blood vessel intima leads to gradual stenosis and impeding blood flow through tissues and eventually results in broad spectrum of clinical manifestations. Clinical manifestations are the consequence of plaque rupture which induce trombogenesis and formation of thrombus and embolus. In this way, the process of thrombogenesis is followed by obstruction of blood vessels. Elimination of risk factors such as obesity, hyperlipidemia and hypertension, improves endothelial function and reduces progression of atherosclerosis. Acta Medica Medianae 2007;46(1):25-29.

Key words: atherosclerosis, risk factors, plaque evolution


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