Početna strana |Uredništvo | Časopis  | Uputstvo autorima  | Kontakt  |  

Acta Medica Medianae
Vol. 46, No 1, January, 2007
UDK 61
YU ISSN 0365-4478

Correspondence to:
Rade R Babić

Institut za radiologiju Kliničkog centra u Nišu

Bulevar dr Zorana Djindjića 48

18000 Niš, Srbija

Copyright 2007 by Faculty  of Medicine, University of Nis


Rade R Babic

Institut za radiologiju Kliničkog centra u Nišu


During urography (IVU) or any other kind of endographic examination, adverse reactions can develope during or immediately after intravascular application of iodine  contrast media (ICM) of which some endanger the patients’ health and life. The aim of the paper was to present adverse reactions of an organism to ICM. That is why the current interest in this problem has imposed to us a necessity to present this study.

In the period from January 1994 to December 2005. in a Specialized Department of the Institute of Radiology of the Clinical Centre Nis, 11.885 IVU were done. An urographyc examination was performed with ionic or nonionic ICM of the same concentracion (300 mg I/ml) or an approximate to it, in the dosage of 1,0 ml/kg. Before intravenous aplication (iv), ICM was heated to body temperature. Application of ICM was done through the braunile, as a slow bolus, in the course of 1-1,5 min.  

In the series of 11.885 urographic examinations, there were severe adverse reactions in 17 patients (0,14% ili 1:699 IVU). There was no fatal outcome.

Adverse reactions at our clinic that could have ended up with lethal outcome, with proper and prompt treatment ended with satisfactory results, so they were registered as severe reactions. Acta Medica Medianae 2007;46(1):52-55.


Key words: iodic contrast media, adverse reactions, urograph

Fulll text