Acta Medica Medianae
Bul. dr Zorana Đinđića 9/2
18000 Niš, Srbija
Copyright 2008 by Faculty of Medicine, University of Nis
EFFECT OF THE HEMODIALYSIS DURATION, AGE AND GENDER ON THE EMERGENCE OF THE RENAL OSTEODYSTROPHY SYMPTOMS
Nemanja Jonjic, Vidojko Djordjevic, Nebojsa Djordjevic and Stanimir Ljubenovic
The study comprises 185 patients who are at the hemodialysis (HD) in the hemodyalitic center of the Clinic for Nephrology of the Clinical Center Nis. The factors analyzed in the hemodialytic patients are: duration of the hemodialysis according to which the patients were divided into two groups (shorter and longer than 5 years), age on the basis of which the patients were divided into three groups (younger than 30, subjects of 30 to 60 years of age and older than 60) and gender. In all 185 hemodialytic patients the most frequent symptoms of renal osteodystrophy were examined on the basis of visualization and the use of verbal symptoms score (VSS). For the statistical processing, the student t-test and the Mantzel Haencel tests were used while the differences at the levels p < 0.01 and p<0.05 were taken as statistically significant and were shown in diagrams and tables. The results of the research showed that of a significantly higher frequency and intensity of pain in the bones, muscles and joints as well as the emergence of spontaneous fractures and/or skeletal deformations in the group which is on the HD for more than 5 years, while the emergence of itching, fatigue and wearisome walking were insignificant with respect to the group which was on the HD for less than 5 years. The impact of gender upon the emergence of subjective symptoms of renal osteodystrophy did not show any significance, while the influence of old age showed statistical significance for the emergence of pain in the bones, muscles and joints in addition to spontaneous fractures and/or skeletal deformations in the group of examinees of 30 to 60 years of age and older than 60. Acta Medica Medianae 2008;47(4):19-24.
Key words: symptoms, renal osteodystrophy,hemodyalisis,age, gender