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Acta Medica Medianae
Vol. 48, No2 , April, 2009
UDK 61
YU ISSN 0365-4478


Correspondence to:
Velimir Kostic

Clinic of Infectious Diseases, Clinical Center

18000 Nis, Serbia






Case report


Hepatitis toxica- Case report


Velimir Kostic, Gordana Trifunovic, Marina Djordjevic, Branislav Jovanovic, Jovana Djordjevic, Jelena Radovic and Lidija Popovic


Clinic of Infectious Diseases, Clinical Center Nis


Toxic lesion of the liver is a subject of differential diagnosis of infectologists-hepatologists. This problem is augmenting because of the abuse of drugs and self-treatment.

   Liver damage mostly goes as cholestatic form of disease, with clinical manifestations of icterus, pruritus, changes of urine and stool color. Clinical finding is followed by quite characteristic laboratory changes (bilirubin, alkaline phospatase, gamma-glutamyl  transpeptidase, cholesterol). In order to make the diagnosis of these patients complete, it is necessary to perform the liver biopsy.  The paper presents the case of a 42-year-old female patient with the syndrome of cholestasis, and clinical, laboratory and pathohistologically confirmed toxic lesions of the liver. Acta Medica Medianae 2009;48(2):49-51.


Key words: toxic hepatitis, medicines