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Acta Medica Medianae
Vol. 49, No 3, September, 2010

UDK 61
ISSN 0365-4478(Printed version)
ISSN 1821-2794(Online)


Correspondence to:

Biljana Miljković-Selimović

Institut za mikrobiologiju i imunologiju

Medicinski fakultet Univerziteta u Nišu

Bul. dr Z. Đinđića 81, 18000, Niš

Republika Srbija

E-mail: biljams@eunet.rs





Review article
UDC:  579.842:616.981.49




Biljana Miljković-Selimović1,2, Tatjana Babić1,3 and Predrag Stojanović1,2



                       National Referent Laboratory for Campylobacter and Helicobacter1

                       Institute of Microbiology and Immunology, Faculty of Medicine in Niš2

                       Center for Microbiology, Public Health Institute Niš3




Salmonella enterica subspecies enterica serovar Enteritidis (S. Enteritidis) has been recently recognized as a prevalent cause of alimentary toxi-infection worldwide. Its widespread presence could be explained by intensification and globalization of traffic, global trade, and the rest of socioeconomic processes. However, no matter to global spreading of S. Enteritidis, there is unequal distribution of certain phage types (PT) where PT 4 and 8 are predominant. Salmonella is considered as a cause of various diseases from acute enterocolitis to typhoid fever. All bacteria from this species have numerous virulence factors such as: adhesins, toxins, virulence plasmids, and cell wall lipopolysaccharides (LPS). Similar to other salmonella serotypes, S. Enteritidis has a virulence plasmid. It allows a bacterium to persist inside the reticuloendothelial cells, while strains without it are eliminated quickly. In the last few years several virulent S. Enteritidis strains of PT 4 were described and considered to be of the same origin. The domination of PT 4 is probably subjected to the resistance of certain strains to nitrofurantoin which is used in poultry rising. The increased significance of S. Enteritidis refers not only to its association with pandemic problems but to frequent reports about extraintestinal infectious processes caused by this bacterium. Taking into consideration that eggs are very important source of infection besides poultry meat, the advised efficient preventive measures, among others, should be some changes in poultry meat preparation, investigation of outbreak-related flocks and devastation of infected ones, as well as egg pasteurization. Acta Medica Medianae 2010;49(3):71-75.


Key words: salmonella enteritidis, infection, virulence factors