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Acta Medica Medianae
Vol. 51, No 4, December, 2012

UDK 61
ISSN 0365-4478(Printed version)
ISSN 1821-2794(Online)


Correspondence to:

Maja Petrović

Department of Ophthalmology

Clinical Center Niš

Bulevar Dr Zorana Đinđjica 48

18000 Niš, Serbia

Original article                                                    

UDC: 616.12-07:577.112




Potential role of visually evoked potential and electroretinography "pattern" in the diagnosis of primary open-angle glaucoma


Maja Petrović1, Predrag Jovanović1, Marija Trenkić Božinović1, Lidija Bojović1

and Marina Jolić2



                      Department of Ophthalmology, Clinical Center Niš1

                      Mental Health Institute, Clinical Center Niš2



Glaucoma is a widely distributed progressive optic neuropathy characterized by progressive damage and loss of retinal ganglion cells of the retina and optic nerve, optic disc excavation increasing and usually, but not always, high intraocular pressure, which eventually results in gradual changes in the visual field.  In our study, we tried to determine the potential role and place of electrophysiological researches (PERG and VEP) in the early detection of glaucoma optic neuropathy, comparing the electrophysiological parameters (P100 and A) and numeric parameters in ophthalmic patients studied. The results obtained in our study show that the application of PERG methods detects early damage to the retinal ganglion cells, whereas the same changes were not observed by VEP analysis, suggesting a potential role of predictive PERG analysis in the early diagnosis of pre-perimetric glaucoma. Acta Medica Medianae 2012;51(4):19-25.


      Key words: glaucoma, PERG analysis, VEP analysis