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Ashok Kumar, B.S.
Department of Pharmacognosy
Sri K.V.College of Pharmacy,
Chickballapur, Karnataka- 562101, India.
IN VITRO ANTIOXIDANT AND α-AMYLASE INHIBITION ACTIVITIES OF PANCHSAKAR CHURNA
Ashok Kumar B.S.1., Gopi Setty Saran2, Firdose Banu1, Harshada R1., Archana P.G.1
Department of Pharmacognosy, Sri K.V. College of Pharmacy, Chickballapur, Karnataka, India1
Department of Pharmaceutics, Sri K.V. College of Pharmacy, Chickballapur, Karnataka, India2
Panchsakar Churna is the composition of Cassia angustifolia, Terminalia chebula, Zingiber officinale, Foeniculum vulgare and Saindhava lavana. Aqueous extract of churna was used to investigate antioxidant activity by ferrous ion chelating assay and ferric reducing power and alpha amylase inhibition activity by dinitrosalicylic acid method (DNSA). Aqueous extract of churna showed maximum ferrous chelating activity - 42.01 and ferric reducing power - 1.5 and 83.33 % of inhibition protein denaturation at 1000 µg/ml. Panchsakar churna showed significant antioxidant and alpha amylase inhibition activities. Acta Medica Medianae 2013;52(4):12-14.
Key words: percutaneous coronary intervention, stent thrombosis