ACTA FAC. MED. NAISS. 2003; 20 (2): 115-120

Review article

b– LACTAM ANTIBIOTICS

²Jović Zorica, ¹Cekić Snežana

¹Department of pharmacology and toxicology Faculty of medicine Niš

²Department of physiology Faculty of medicine Niš

SUMMARY

b-lactam antibiotics are useful and frequently prescribed antibiotics that share a common structure and mehanism of action-inhibition of the bacterial peptidoglycan cell wall. Important classes of penicilins include penicilin G and V, which are highly active against susceptible gram-positive cocci; penicillinase-resistant penicillins such as nafcillin, which are active against penicillinase-producing Staphylococcus aureus; ampicillin and other agents with an improved gram-negative spectrum; and extended spectrum penicillins with activity against Pseudomonas aeruginosa, such as ticarcillin and piperacillin.

Key words: b-lactam antibiotics, pencilin G, penicillin V.