ACTA FAC MED NAISS 2009;   26 (2): 105-109

Case report

PYODERMA GANGRENOSUM - CASE REPORT

Jelica Tiodorovic, Viktor Lazarevic, Radmila Milenkovic, Danica Tiodorovic-Zivkovic

Clinic for Dermatovenerology,
Clinical Centre Nis


SUMMARY

Pyoderma gangrenosum (PG) is a rare, inflammatory, non-infective, non-neoplastic skin disorder, which is often associated with systemic diseases (1). Etiology of PG is still unknown.
The paper presents the case of a 23 year-old male patient with skin lesions localized on the skin of the face, ear lobe, neck, chest and back. There were numerous pustules, papules, vesicles and blisters filled with hemorrhagic content, and shallow ulcers covered with dark yellow crusts.
The patient had been treated from ulcerative colitis for year and a half prior to skin lesions.
After starting the therapy with Cyclosporine accompanied with low doses of corticosteroids, the overall condition of our patient improved, the number of stools was reduced, and the ulcers on the skin began to epithelize. There have not been new lesions in our patient during these 11 months of follow- up.

Key words: pyoderma gangrenosum, ulcerative colitis, cyclosporine