ACTA FAC
MED NAISS 2011;28(2):135-138|
ACTA FAC
MED NAISS 2011;28(2):135-138 |
Case report
UDC:616.155.392-085:616-036.88
Hyperlymphocytosis in a Patient with T-prolymphocytic Leukemia Not Responding to Therapy: Case Report
Goran Marjanović1,2, Vesna Nikolić1, Tomislav Vukićević1, Lana Mačukanović Golubović1,2, Dragana Drašković1
1Clinic of Hematology and Clinical Immunology, Clinical Centre Niš, Serbia
2University of
Niš, Faculty of Medicine, Serbia
SUMMARY
A 64-year-old patient with extremely high number of white
blood cells was diagnosed with T prolymphocytic leukemia. After the initiation
of chemotherapy with Cyclophosphamide, Oncovin, Doxorubicin and Prednisone
(CHOP), there was no improvement and the patient died within two months. Authors
have made a review of the current therapy of this rare disorder of mature
T-lymphocytes and discussed various therapeutic aspects of hyperlymphocytosis.
Key words: T-cell prolymphocytic leukemia, hyperlymphocytosis, therapy