ACTA FAC MED NAISS 2014;31(1):51-58

Original article

UDC:616.36-002(497.11)

DOI:10.2478/afmnai-2014-0005

Epidemiological Characteristics of Carriers of Antibody Against Hepatitis C Virus

in the Population of Nišava District

Marina Kostić¹, Biljana Kocić^1,2, Lidija Popović Dragonjić^2,3

¹Public Health Institute Niš, Serbia

²University of Niš, Faculty of Medicine, Serbia

³Clinic of Infectious Diseases, Clinical Centre Niš, Serbia


summary

The aim of the paper was to determine the disease trends and characteristics of anti-HCV antibody carrier status for the purpose of better prevention and disease control. The materials used were annual reports, reports of diseases and deaths from infectious diseases, and epidemiological surveys of the Public Health Institute Niš in the period from 2002 to 2011 in the Nišava District. A descriptive epidemiological method was used. Rates were non-standardized and were calculated per 100.000 residents. There was an upward trend (y=-5.4+8.21 x±R²=0.53) of HCV carriers. Most carriers were male (68.34%), from urban areas (81.66%), aged 37.75±SD 16.80 years on the average, and unemployed (39.45%) (out of which the inmates of the Correctional Facility in Niš making up 26.11%). More than half of the registered carriers (59.05%) were not able to report the precise mode of transmission. Then followed hemodialysis patients (15.83%), injecting drug users (11.06%), blood donors (4.77%), pregnant women (3.52%), mother-to-child transmission cases (2.26%), and health professionals (0.75%). There were 14.82% of hospitalized cases. In 4.52%, a coinfection with hepatitis B virus was found. HCV carrier status in the Nišava District showed an upward trend. Low incidence rates might have been the result of underreporting. Since there is no anti-HCV vaccine, it is necessary to focus on the activities of health education of all categories of people at risk, as well as on the service providers in different sectors, risk factors, modes of transmission and protection measures.

Key words: epidemiology, carriers, HCV antibodies, trend