ACTA FAC MED NAISS 2019;36(3):207-218

Original article

UDC: 616.831-005.1-082-036.82

DOI: 10.5937/afmnai1903208L

Association of Parameters of Hospital Admission and the Level of Functional Recovery in Conservatively Treated Patients with Spontaneous Brain Hemorrhage

Srdjan Ljubisavljević^1,2, Aleksandra Ignjatović^1,3

¹University of Niš, Faculty of Medicine, Niš, Serbia
²Clinic of Neurology, Clinical Center Niš, Niš, Serbia
³Public Health Institute, Niš, Serbia

summary


The aim of the paper was to identify the correlation between the parameters of hospital admission and clinical outcome in nontraumatic intracerebral hemorrhage (ICH) patients younger than 65 years, who were not surgically but conservatively treated only. The analyzed data was collected from the medical records of 341 consecutive patients who suffered a non-traumatic ICH and were conservatively treated. Demographics, medical history, clinical, radiological and biochemical variables on hospital admission and other relevant findings were analyzed in reference to functional outcome of non-traumatic ICH (measured on discharge from hospital). The following parameters were recognized as the predictors of fatal clinical outcome: lower values of GCS (OR 0.686, p = 0.023), high values of NIHSS (OR 1.258, p < 0.001), body temperature on hospital admission (OR 1.896, p = 0.034), absence of headache in ICH clinical presentation (OR 0.298, p = 0.012) as well as the sedimentation rate (OR 1.028, p = 0.045). The predictors of good clinical outcome after ICH were as follows: high values of GCS (OR 1.876, p = 0.032), lower values of NIHSS (OR 0.841, p = 0.002) and persistence of headache in ICH clinical presentation (OR 5.115, p = 0.001). Recognition of predictive factors could help to identify the patients at high risk of ICH progression and can help in the selection of pathogenetic therapy that could minimize the possibility of ICH progression.

Key words: brain hemorrhage, functional recovery