ACTA FAC MED NAISS 2020;37(1):48-56

Original article

UDC: 687.552.2:615.454.1:613.99
DOI: 10.5937/afmnai2001048N

Investigation of Efficacy of Anti-Aging Liposomal Intimate

Gel: An In Vivo Long-Term Study

Ivana Nešić, Vesna Savić, Ana Kolarević

University of Niš, Faculty of Medicine, Department of Pharmacy, Niš, Serbia

summary


    Liposomes have been used as universal carriers for decades, encapsulating many compounds with different cosmetic effects in order to achieve the quality, safety and efficacy of functional cosmetic products. In the present study, the efficacy of the application of the commercial liposome gel (SOPHY Anti-Aging Liposomal Intimate Gel), containing L-arginine, white curcuma extract, hyaluronic acid, lactic acid and vitamin E (previously shown to have various positive effects on the skin) as encapsulated cosmetic active ingredients, was examined in vivo on healthy volunteers. During a long-term 28-day study, biophysical skin parameters (skin humidity, TEWL, EI and pH) were monitored. As a result, an increase in skin hydration, decrease in TEWL, and a slight decrease in EI and skin pH were observed. Thus, the examined cosmetic product has shown a positive effect on skin hydration, contributing to the renewal of skin barrier, also having the anti-irritating effects.

Key words: liposomal intimate gel, efficacy, in vivo study, biophysical skin parameters