Impact of Anesthesia on the Development
of
Postoperative Delirium
Marija Stošić1,2,
Velimir Perić1,2, Jelena Živadinović1,3,
Aleksandar Kamenov1,2,
Vladimir Stojiljković1,2, Dragan Milić2, Milan
Lazarević1,2, Aleksandar Nikolić1,3,
Dalibor Stojanović1,2, Mlađan Golubović1,2
1Univeristy of Niš, Faculty of Medicine, Niš,
Serbia
2University Clinical Center Niš, Clinic for
Cardiosurgery, Niš, Serbia
3University Clinical Center Niš, Clinic for
Anesthesia and Intensive Care, Niš, Serbia
SUMMARY
Introduction/Aim. Postoperative delirium is defined as an acute
state of confusion that develops within hours or days after surgical
intervention. With the global aging of the world population, the
number of geriatric patients who will undergo surgery is on a steady
rise, increasing therefore the possibility of postoperative
delirium. The primary aim of this study was to determine the effect
of age, type of surgical procedure, as well as the type of
anesthesia on postoperative delirium.
Methods. The investigation was performed in the form of a
prospective study. Patients who underwent general and regional
anesthesia were included. Benzodiazepines and atropine were used for
premedication; from among intravenous anesthetics, propofol was used
for hypnosis and from inhalation anesthetics sevoflurane; for
analgesia, opioids were used. Bupivacaine was used to administer
regional anesthesia.The level of cognitive functioning was tested
using two tests: the Mini Mental Examination in the preoperative
period and the CAM-ICU in the postoperative period.
Results. Using the t-test for independent samples, it was found that
there was a statistically significant difference between the two age
groups of patients. It was found that there was no statistically
significant difference in terms of cognitive functioning between
patients who received general anesthesia and those who received
regional anesthesia. The results of the analysis showed that there
was no statistically significant difference between groups who
received different types of surgery.
Conclusion. The practical value of this study is that the
preparation of patients for these types of abdominal interventions
can follow the general guidelines.
Keywords: anesthesia, delirium, elderly
patients
Corresponding author:
Marija Stošić
e-mail:
marija91nis@gmail.com