ACTA FAC MED NAISS 2010; 27(4):215-220

Review article

UDC: 616.155-006.4:612.118-089.843

Cord Blood Transplantation in Adult Patients With Hematological Malignancies

Goran Marjanović¹, Milena Todorović-Bakrač², Tatjana Jevtović-Stoimenov³

¹Clinic of Hematology and Clinical Immunology, Clinical Centre Niš, Niš, Serbia

²Institute of Hematology, Clinical Centre of Serbia, Belgrade, Serbia

³Institute of Biochemistry, University of Niš, Faculty of Medicine, Niš, Serbia


SUMMARY

The purpose of this review was to show the available clinical and biological advances of umbilical cord blood allogeneic stem cell transplantation in adult patients. In adults, umbilical cord blood transplantation, due to less pronounced graft versus host disease compared to conventional approaches may, be feasible in spite of slower engraftment. The authors discussed certain attempts for improvement of umbilical cord stem cells engraftment.

Key words: umbilical cord transplantation, unrelated stem cell transplantation