2Pelvic Ring Injuries

Running title: Psychoactive Substances and Kidneys

The Influence of Psychoactive Substances on Nephrotoxicity of the Kidneys

Radojica Stolić¹, Marija Milić², Vekoslav Mitrović³, Andrijana Karanović²,
Kristina Bulatović², Dragiša Rašić², Milica Mirović⁴, Branka Mitić^5,6

¹University of Kragujevac, Faculty of Medical Sciences, Department of Internal Medicine, Kragujevac, Serbia
²University of Priština Settled in Kosovska Mitrovica, Faculty of Medicine, Kosovska Mitrovica, Serbia
³University of East Sarajevo, Faculty of Medicine Foča, Republika Srpska, Bosnia and Herzegovina
⁴University Clinical Center Kragujevac, Clinical of Nephrology and Dialysis, Kragujevac, Serbia
⁵University of Niš, Faculty of Medicine, Niš, Serbia
⁶University Clinical Center Niš, Clinic of Nephrology, Niš, Serbia

SUMMARY

Background/Aim. The metabolism and effects of the abuse of psychoactive substances are not yet fully understood, but it is evident that they represent a tremendous risk to the health of individuals. This paper aims to present a review of published results on the impact of psychoactive substance abuse on kidney function.

Methodology. PubMed and MEDLINE databases were used to search the literature related to drug abuse and its effects on renal function.

Results. For this study, we found 79 human studies that aimed to present a summary of published results on the impact of psychoactive substance abuse on kidney function. Renal manifestations of specific illicit drug abuse were included in this review.

Conclusion. Understanding the nephrotoxicological profile caused by the use of psychoactive substances is the basis for adequate risk assessment and improvement of the treatment of consequential kidney disorders.

Keywords: abuse, psychoactive substances, kidney disease, nephrotoxicity, complications

Corresponding author:

Radojica Stolić

e-mail: radojica.stolic@med.pr.ac.rs