INCIDENCE OF HEART FAILURE IN DIABETICS WITH CORONARY HEART DISEASE
Heart failure (HF) on the basis of coronary heart disease (CHD) is leading cause
of mortality in 37‡62% diabetics. In diabetics CHD is associated with
hypertension, central obesity, dislipidemia, hyperfibrinogenemia etc.
The aim of this paper was to examine incidence of heart failure in diabetics
with CHD, as well as its clinical characteristics compared with nondiabetic
patients.
We analyzed 478 patients with CHD and exclude patients with, hypertension,
dislipidemia, cardiovascular diseases, smokers and other heart failure
threatening diseases. We formed two groups with 30 diabetics and 30
nondiabetics.
There is no difference in age between gendesr in diabetics. Nondiabetics males
with CHD 45±4.2 year are younger than females 56.2±4.6 (p<0.01). About 33.3%
diabetics have heart failure (HF), and 20% nondiabetics, which is statistically
important (p=0.1). There is no significant difference in HF incidence between
gender in both groups. Nondiabetics females with HF are more obesity than males
(27.3±1.5 vs. 26.5±1.4kg/m2), as well as in diabetics (33.6±2.6 vs.
30.7±2.1kg/m2), (p<0.05), which is also seen in patients without HF.
Males and females with diabetes mellitus need earlier detection of CHD and
earlier therapy in the aim of prevention of HF. The diabetics with myocardial
infarct need the permanent control and aggressive therapy on appearing of the
first signs of HF. Acta Medica Medianae 2003; 42(1):29-32.
Key words: diabetes, heart failure, coronary heart disease