Acta
Medica Medianae
Vol. 42
Number 1, Januar, 2003
UDK 61
YU ISSN 0365-4478
Contact:
Slavica Veselinović,
Klinika za onkologiju Klinički centar — Niš
Brace Tasković, 18000 Niš, Srbija i Crna Gora
E-mail: vesa@bankerinter.net
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BILATERAL BREAST CANCER
Slavica Veselinović, Stojan
Radić, Branislava Raičević i Anica Stanić
Klinika za onkologiju
Kliničkog centra u Nišu
Incidence and clinical characteristics of women with bilateral breast cancer
treated in the period 1996-1997 at the Clinic of Oncologv in Nish were
analyzed. Out of 741 patients with breast cancer, bilateral disease was
observed in 35 (4.7%) cases. Sinchronous bilateral breast cancer type was
registered in 15 (42.9%), while metachronous cancer occurred in 20 (58.1%)
cases. Clinical characteristics, age distribution, histopathologic status,
tumour grade and survival in patients with bilateral cancer were compared
with the appropriate findings in 35 randomly chosen patients with unilateral
tumour. Average age structure of bilateral breast cancer patients was 51.92
years, while the appropriate value in unilateral cancer group was somewhat
higher, 58.71 years of age. Analyses of the menopausal status, stage of
initial disease, histopathologic features and histologic grade have not
indicated significant differences in frequency regarding unilaterality and
bilaterality of breast cancer. Local relapses and distant metastases were
not different either. Five-year survival was not significantly different in
these two groups too. The analysis of our results demonstrated slightly
higher frequency of metachronous bilateral breast cancer compared to
bilateral tumour type. Statistically significant difference was observed for
the factor of familial patient history in women with bilateral breast
cancer. Acta Medica Medianae, 2003; 42(1 ):57-61.
Key words: bilateral.
breast cancer, sinchronous, metachronous, frequency, clinical
characteristics
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