|Home page     |Editorial  board | About the Journal   | Instructions for Authors | Peer Review Policy | Clinical and Experimental Work Code |   Contact  |  

 

Acta Medica Medianae
Vol. 42
No 2, April, 2003
UDK 61
YU ISSN 0365-4478

 



Contact:
Boris Đinđić
Institute of pathologic phiziology Faculty of Medicine
81 Braće Tasković street,
18000 Niš,
Serbia and Montenegro
Tel.: 018/326-644,
e-mail:
boris_dj@medfak.ni.ac.yu

BIOLOGICAL EFFECTS OF MICROWAVE RADIATION ON BRAIN TISSUE IN RATS

Boris Đinđić1 , Dušan Sokolović2,Stojan Radić1,Tomislav Pavlović3, Mirjana Cvetković 4, Jasmina Radisavljević 4

1 Institute of pathologic phiziology Faculty of Medicine Faculty of Medicine
2 Institute of biochemistry
3 Faculty of sciences and mathematics University of Nis
4 Faculty of Occupational Safety University of Nis

Exposure to microwave radiation induces multiple organ dysfunctions, especially in CNS.

The aim of this work was investigation of biological effects of microwave radiation on rats' brain and determination of increased oxidative stress as a possible pathogenetic's mechanism.

Wistar rats 3 months old were divided in experimental (4 female and 4 male animal) and control group (5 female and 4 male). This experimetnal group was constantly exposed to a magnetic field of 5 mG. We simulated using of mobile phones 30 min every day. The source of NIR emitted MF that was similar to mobile phones at 900 MHz. The rats were killed after 2 months. Biological effects were determined by observation of individual and collective behaviour and body mass changes. Lipid peroxidation was determined by measuring quantity of malondialdehyde (MDA) in brain homogenate.

The animals in experimental group exposed to EMF showed les weight gain. The most important observations were changing of basic behavior models and expression of aggressive or panic behavior. The content of MDA in brain tissue is singificantly higher (1.42 times) in rats exposed to electromagnetic fields (3,82±0.65 vs. control 2.69±0.42 nmol/mg proteins, p<0.01).
Increased oxidative stress and lipid peroxidation after exposition in EM fields induced disorders of function and structure of brain. Acta Medica Medianae 2003; 42 (2): 9-12.

Key words: microwave radiation, lipid peroxidation, brain