Acta
Medica Medianae
Vol. 42
No 2, April, 2003
UDK 61
YU ISSN 0365-4478
Contact:
Boris Đinđić
Institute of pathologic phiziology Faculty
of Medicine
81
Braće Tasković street,
18000 Niš,
Serbia and Montenegro
Tel.: 018/326-644,
e-mail:
boris_dj@medfak.ni.ac.yu
|
BIOLOGICAL EFFECTS OF
MICROWAVE RADIATION ON BRAIN TISSUE IN RATS
Boris Đinđić1
,
Dušan Sokolović2,Stojan Radić1,Tomislav Pavlović3,
Mirjana Cvetković 4,
Jasmina Radisavljević 4
1 Institute of
pathologic phiziology Faculty of Medicine Faculty of Medicine
2 Institute of biochemistry
3 Faculty of
sciences and mathematics
University of Nis
4 Faculty of
Occupational Safety University of Nis
Exposure to microwave radiation induces multiple organ dysfunctions, especially
in CNS.
The aim of this work was investigation of biological effects of microwave
radiation on rats' brain and determination of increased oxidative stress as a
possible pathogenetic's mechanism.
Wistar rats 3 months old were divided in experimental (4 female and 4 male
animal) and control group (5 female and 4 male). This experimetnal group was
constantly exposed to a magnetic field of 5 mG. We simulated using of mobile
phones 30 min every day. The source of NIR emitted MF that was similar to mobile
phones at 900 MHz. The rats were killed after 2 months. Biological effects were
determined by observation of individual and collective behaviour and body mass
changes. Lipid peroxidation was determined by measuring quantity of
malondialdehyde (MDA) in brain homogenate.
The animals in experimental group exposed to EMF showed les weight gain. The
most important observations were changing of basic behavior models and
expression of aggressive or panic behavior. The content of MDA in brain tissue
is singificantly higher (1.42 times) in rats exposed to electromagnetic fields
(3,82±0.65 vs. control 2.69±0.42 nmol/mg proteins, p<0.01).
Increased oxidative stress and lipid peroxidation after exposition in EM fields
induced disorders of function and structure of brain. Acta Medica Medianae 2003;
42 (2): 9-12.
Key words: microwave radiation, lipid peroxidation,
brain |