Acta Medica Medianae
Vol. 42
Number 3, Juli, 2003
UDK 61
YU ISSN 0365-4478



Kontakt:
Zoran Pesić
Katedra za maksilifacijalnu hirurgiju,
Stomatolološka klinika,
Braće Tasković 52,
18000 Niš;
Srbija i Crna Gora
Tel.: 018/530-069
e-mail: zorannp@bankerinter.net

INCIDENCE OF TUMOR CELLS PRESENCE ON HISTOPATHOLOGICAL SPECIMENTS MARGINS IN RELATION TO WIDENESS OF INTRAORAL CARCINOMAS EXCISION

Zoran Pešić*, Dragan Krasić * i Dragan Mihailović**

*  Department for Maxillofacial Surgery, Clinic for Dentistry

Correct surgical therapy considers radical excision of tumor formation, what can be certificated by absence of tumor cells on histopathological specimen margins.
The aim of this investigation is to estimate incidence of presence of tumor cells on histopathological specimen margins in cases of intraoral carcinomas, surgically excised in macroscopically normal tissue with different wideness of normal tissue zone and relation to postoperative survival of this patients with intraoral carcinomas.
Fifty seven patients with intraoral carcinomas were divided in three groups according to wideness of zone of excision in macroscopically normal tissue. Lowest percent of presence of tumor cells on margins of histopathological specimens were ingroup of patients with zone of excision behind zone of indurations of soft tissue, but patients from this group had shortest postoperative survival period. Presence of tumor cells on margins of histopathological specimens of excided intraoral carcinomas was found in high number of 81,07%.
It can be said that presence of tumor cells on margins of histopathological specimens of excided intraoral carcinomas was found in extremely high number of 81,07%, but direct statistical significant relation in-between wideness of surgical excision and postoperative survival period was not found what show that another factors connected with postoperative survival of this patients must be examine. Acta Medica Medianae 2003; 42(3):23-25.

Key words: carcinomas, intraoral, histopathological, margins