Acta Medica Medianae
Vol. 43
Number 1, Januar, 2004
UDK 61
YU ISSN 0365-4478



Contact:
Voja Pavlovic
Institute of Physiology, Faculty of Medicine
81 Dr Zoran Djindjić Street,
18000 Nis, Serbia and Montenegro
Phone: 018/334-221,
e-mail: vojapav@yahoo.com

HE EFFECTS OF ASCORBIC ACID ON MEMBRANE TRANSPORT OF GLUCOSE

Voja Pavlovic*and Zoran Pavlovic**

    The level of glycemia and ascorbic acid was tested of oral glucose-tolerance test (OGTT). This test was done on thirty healthy normoglycemic adult women, between 18 and 30 years of age, who showed no clinical signs of endocrine disturbances.
    At the beginning of the experiment the level of ascorbic acid and the level of glycemia were determined twelve hours after the last meal. In the following seven days eash of the examined women was given, beside the usual nourishment, 1.000 mg ascorbic acid (two times a day of 500 mg with breakfast and lunch). The level of ascorbic acid the last taken dosage of ascorbic acid. The achieved results of OGTT at the beginning and in the end of the test showed the ascorbic acid in the dosage of 1.000 mg/per day for seven days intensified the level glycemia during OGTT.
    This hyperglycemy is probably the consequence of the receptor obstruction in cellular membrane by ascorbic acid. Acta Medica Medianae 2004; 43 (1):39-41.