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Acta
Medica Medianae
Vol. 43
Number 2, April, 2004
UDK 61
YU ISSN 0365-4478
Contact:
Irena Jankovic
Surgery clinic,
Clinical Center,
48 Dr Zoran Djindjic Street,
18000 Nis, Serbia and Montenegro
Phone: 064/2752303,
e-mail: dimitry7@eunet.yu
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THE ANALYSIS OF DIMENSIONS AND THE RATE OF RECURRENCE OF BASAL CELL CARCINOMA
OF PERIORBITAL REGION AFTER EXCISIONAL SURGERY
Irena Jankovic*,
Milan Visnjic*,
Dragan Mihailovic** and
Dimitrije Jankovic***
Surgery clinic, Clinical Center, Nis* Pathology clinic, Clinical Center,
Nis** PharmaSwiss, Belgrade***
Basal cell carcinomas (BCC) of periorbital region are often seen in clinical
practice and have a potential risk of local recurrence.
This research has been done at the Surgery clinic in Nis - Department of plastic
and reconstructive surgery and at the Pathology clinic. 101 patients who had
surgery in period from 2000 to 2003, had been analysed. 12 patients had multiple
located tumours, so the total number of observed tumours was 121. Tumours have
been devided in two groups, depending if they are primary or recurrent: first
group - primary tumours (n=111), second group - recurrent tumours (n=10).
Patients with recurrent BCC were 56,7 years of age. It is significally less than
in patients with primary BCC of periorbital region. They were 66,407 years of
age (p=0,037). Ten tumours were recurrent (8,3%). The greatest number of
recurrencies was on medial canthus (40%), then on upper eyelid (30%), on lower
eyelid (20%), and on lateral canthus (10%). Tumours larger than 2cm in radius
have predispositions to recurrence (p=0,01). There is a positive correlation
between surface and thickness of tumours (p<1x10-6). There is a positive
correlation between the depth of histologic layer to which tumour has penetrated
and thickness of tumour (p=0,018).
The average age of patients with recurrence is significally lower than average
age of patients with the primar tumour. By defining size and location of BCCs of
periorbital region, it is possible to predict biological behaviour of tumour.
Acta Medica Medianae 2004; 43(2): 13-18.
Key words: basal cell carcinoma, periorbital region, recurrence
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