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Acta Medica Medianae
Vol. 43
Number 3, July, 2004
UDK 61
YU ISSN 0365-4478

 

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Institute of fiziology,
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18000 Niš,
Serbia and Montenegro
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Copyright 2004 by Faculty  of Medicine, University of Nis

THE EFFECTS OF ASCORBIC ACID ON MEMBRANE TRANSPORT OF GLUCOSE


Voja Pavlovic* and Zoran Pavlovic**

Institute of fiziology, Faculty of Medicine, Niš
Clinic of Hematology, Medical Center, Niš


In this study we compared the effects of ascorbic acid on the glucose levels in the plasma.

At the beginning of the experiment the level of ascorbic acid and the level of glycemia were determined twelve hours after the last meal. In the following seven days each of the examined women was given, beside the usual nourishment, 1000 mg ascorbic acid (two times a day of 500 mg with breakfast and lunch). The level of ascorbic acid and glycemia was determined on the eight day of the experiment, twenty-four hours after the last taken dosage of ascorbic acid. The achived results of oral glucose - tolerance test (OGTT) at the begining and in the end of the test were shown in a table and on a diagram.
The intake of ascorbic acid in the dosage of 1000 mg/a day for seven days, intensifies the level of glycemia during OGTT.

This hyperglycemia is probaly the consequence of receptor obstruction in cellular membrane by ascorbic acid. Acta Medica Medianae 2004; 43(3): 29-31.


Key words: ascorbic acid, glycemia, vitamin C