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Acta
Medica Medianae
Concat:
Copyright 2004 by Faculty of Medicine, University of Niš |
ACUTE MYOCARDIAL INFARCTIONTHERAPY IN WOMEN
Ružica
Janković*,
Milan Pavlović*,
Svetlana Apostolović*,
Danijela Djordjević-Radojković*,
Although after the AHA/ACC recommendations there should be no sex differences regarding the diagnostic and therapeutic procedures in acute coronary syndrome and secondary prevention of coronary disease (CD), they still persist not only in our country but also in other, much more developed and equipped hospitals of the West. It has been demonstrated that the discrepancy is primarily conditioned by the advanced age of women and consequently advanced cardiac status at CD presentation, as well as a greater burden of comorbidity in this patient population. Aim of this paper was to assess the sex differences in therapeutic approach in our patients with their first acute myocardial infarction. The investigation enrolled 320 patients (94 women and 226 men) treated in the Coronary Unit, Clinic for Cardiovascular diseases, Clinical Center Nis in the acute phase of the first myocardial infarction. In the experimental sample women were significantly older than men (62,95 ± 8,16 vs 57,73 ± 10,24; p<0,0001). Based on the stratification of both sexes into the age groups, it was demonstrated that there were significantly less women with acute myocardial infarction (AIM) below 55 years of age, and significantly more in more advanced age groups (between 65 and 74 years of life). Compared to men, it was observed that women with AIM significantly less often received fibrinolytic therapy (40% vs 58%; p<0,05). Average age of women receiving fibrinolytic agents was 65,67±8,69 years and men 56,09±10,7, which was of statistical significance (p<0,05). There were no significant differences regarding other groups of drugs. Medicamentous treatment of AIM in our country follows the up-to-date recommen-dations of European and worldwide associations of cardiologists. The only difference observed was infrequent use of fibrinolytic therapy in women due to sex-conditioned reasons, including different AIM presentation, patient age and complication proneness. Acta Medica Medianae; 43(4): 75–80.
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