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Acta
Medica Medianae Concat:
Copyright 2004 by Faculty of Medicine, University of Niš |
THE
SIGNIFICANCE OF PATTERN ERG IN CENTRAL VEIN OCCLUSION
Dragan Veselinović*,
Stojanka Đurić**,
Zlatica Višnjić*,
Saša Novak* and
Marija Trenkić* Opthamology Clinic,
Clinical center, Niš*
Pattern
electroretinogram (PERG) findings were analysed in 30 patients with central
retinal vein occlusion. Latency and amplitude values of PERG waves were compared
with the results obtained in 30 healthy individuals after sample
randomisation. In 15 cases with „hemorrhagic type” occlusion of the central
retinal vein significantly reduced N1-P1 wave amplitude was noted (0,369 mV),
related to „exudative“ disease type (0,557 mV), as well as to the control group
of examines (0,782 mV). PERG was described as the sensitive method and important
indicator in damage assessment, ie. ischemia in the ganglional cell layer in
central retinal vein occlusion. Ischemia increases anoxia, which influences not
only the axons but also the enzymatic and transport processes within the cell
bodies, dendrites, axons and axonal terminals. Slowing down of the fast phase of
axoplasmatic transport in the axons in ischemic damage blocked transmission
impulses which could be evident through different degrees of PERG wave amplitude
reduction. With this method the patients can be selected in whom due to severe
retinal ischemia there is the risk of neovascular glaucomma and maculopathy,
which is the absolute indication for panlaser-photocoagulation.
Acta Medica
Medianae 2004; 43 (4): 31–34. Key words: PERG, central retinal vein occlusion |