DIRECTIONS IN THE
EVOLUTION OF CERVICAL L-SIL LESIONS
Molecular
activities in the basic cytopathological substratum of the lesions on utherus
cervicus, in case of HPV infection in form of squamous intraepithelial lesions
of the low (L - SIL) and high (H - SIL) level, are defined by bathesda
therminological system. More frequent, L - SIL changes include CIN I, coil
atypia and condilomata lata and can be recognized by cellular abnormalities in
the basal and parabasal layer with minor cellular structural changes , nuclei
hyperhromasia with hromatin condensation, acantosis, paraceratosis with well
differentiated cells and faster exfoliation. Women more prone to develop L-SIL
are those older than 41, with III degree of vaginal secretion, with the
colposcopic finding of aceto-white epithelium and Papa-Nicholaus test of III
group. The control cervical, colposcopically controlled biopsy was resumed after
four control medical check-ups done every three months after the L-SIL
diagnosis. The results showed that lesions remained at the same stage (41,67%),
whereas regression appeared in every third examinee (33,33%), slight progression
in every eight examinee (12,50%), and significant progression in every twelfth
examinee (8,33%).Our conclusion was that L-SIL lesions do not require the
ablativ therapy a priory, and what is needed is a regular colpocytological
check-up every three months and cervical biopsy, if necessary. Diagnosis of HPV
infection certainly changes one’s attitude and requires loop diameter because of
the additional diagnostic indications and final therapy. Acta Medica Medianae
2005; 44 (1):11-14.
Key words: cervix, L-sil lesions, evolution