Acta Medica Medianae
Vol. 48, No3, October, 2009
UDK 61
YU ISSN 0365-4478
 

Correspondence to:

Aleksandar Veselinović
Klinika za očne bolesti Kliničkog centra
Bul. dr Zorana Đinđića 48 Niš
Tel.:018 332-367
E-mail:vesaboy81@hotmail.com

Review article
UDC: 617.7-006.4

OCULAR MANIFESTATIONS OF TYPE 1 NEUROFIBROMATOSIS

Aleksandar Veselinović¹, Dragan Veselinović¹, Zoran Radovanović², Mila Bojanović³, Vasko Bulatović¹ i Marija Veselinović¹

Ophthalmology Clinic, Clinical Center Niš¹
Institute of Radiology, Clinical Center Niš²
Otorhinolaryngology Clinic, Clinical Center Niš³

Ocular type 1 neurofibromatosis is an autosomal dominant phacomatosis with variable expression and the occurrence of characteristic changes in the eye. The most frequent ophthalmologic finding in the eye is the presence of characteristic iris nodules. The shared result also describes the neurofibromatosis of the upper eyelid, an optic nerve glioma, choroidal hamartomas as well as congenital glaucoma. In addition, the paper gives a detailed presentation of a patient with type 1 neurofibromatosis, with the characteristic changes on the skin, which spread on the central nervous system and characteristic changes in the eye and its adnexa.
It is also points out how much a detailed ophthalmologic examination is essential for detecting and recognizing possible manifestations, as well as criteria for making correct diagnoses of ophthalmologic diseases. Furthermore, the paper presents criteria for making diagnoses of type 1 neurofibromatosis in detail, taking into account a large number of manifestations on different organs. Acta Medica Medianae 2009;48(3):38-42.

Key words: type 1 neurofibromatosis, ocular manifestations