Acta Medica Medianae
Vol. 52, No 4, December, 2013
UDK 61
ISSN 0365-4478(Printed version)
ISSN 1821-2794(Online)
 

Correspondence to:

Ashok Kumar, B.S.

Department of Pharmacognosy

Sri K.V.College of Pharmacy,

Chickballapur, Karnataka- 562101, India.

E-mail: ashok4vani@gmail.com

Original article                                                                                  

UDC: 615.322:577

doi:10.5633/amm.2013.0402

IN VITRO ANTIOXIDANT AND α-AMYLASE INHIBITION ACTIVITIES OF PANCHSAKAR CHURNA

Ashok Kumar B.S.¹., Gopi Setty Saran²,  Firdose Banu¹, Harshada R¹., Archana P.G.¹

Department of Pharmacognosy, Sri K.V. College of Pharmacy, Chickballapur, Karnataka, India¹

Department of Pharmaceutics, Sri K.V. College of Pharmacy, Chickballapur, Karnataka, India²

Panchsakar Churna is the composition of Cassia angustifolia, Terminalia chebula, Zingiber officinale, Foeniculum vulgare and Saindhava lavana. Aqueous extract of churna was used to investigate antioxidant activity by ferrous ion chelating assay and ferric reducing power and alpha amylase inhibition activity by dinitrosalicylic acid method (DNSA). Aqueous extract of churna showed maximum ferrous chelating activity - 42.01 and ferric reducing power - 1.5 and 83.33 % of inhibition protein denaturation at 1000 µg/ml. Panchsakar churna showed significant antioxidant and alpha amylase inhibition activities. Acta Medica Medianae 2013;52(4):12-14.

      Key words: percutaneous coronary intervention, stent thrombosis