Original article                                                                            UDC: 616.345-002-089:579.86                                                                                                             doi:10.5633/amm.2015.0113

 

  

Clostridium difficile colitis - a role of surgery

 Ladislav Mitáš¹, Tomáš Skřička¹, Zdeněk Kala¹, Pavel Polák², Igor Penka¹,
Markéta Hansliánová³, Beáta Hemmelová¹

 

Surgical Clinic of University Hospital Brno and Faculty of Medicine,

Masaryk University Brno, Czech Republic¹

Clinic of Infectious Diseases of University Hospital Brno and Faculty of Medicine,

Masaryk University Brno, Czech Republic²

Department of Clinical Microbiology of University Hospital Brno and Faculty of Medicine,

Masaryk University Brno, Czech Republic³

 

                       Contact: Tomas Skricka
                      Surgical Clinic of University Hospital Brno
                      Masaryk University Brno, Czech Republic
                      t.skricka@gmail.com

 

Clostridium difficile infection (CDI) is the most frequent cause of nococomial diarrhoea. Most cases are succesfully treated by antibiotic therapy, but nearly 10% may progress to the fulminant form. The aim of this work is a retrospective evaluation of the results of surgical treatment of patients with the severe Costridium colitis, in the period 2008-2014.

Clostridium toxins were detected in patients in Bohunice University Hospital in 1956. Thirty seven of them underwent surgery due to toxic colitis. There were 6 total colectomies with terminal ileostomy, 29 subtotal colectomies with terminal ileostomy, 1 coecostomy and 1 axial ileostomy. The 30-day mortality was nearly 35 %, 90- day mortality 54% and morbidity 89%.

Early and precise indication for surgery could save about 65% of patients with fulminant course of Clostridium difficile colitis. Acta Medica Medianae 2015;54(1):75-80.

 

Key words: Clostridium difficile colitis, toxic colitis, surgery