TREND OF THE INCIDENCE

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ACTA
STOMATOLOGICA
NAISSI

Table of Contents for
Decembre 2017 • Volume 33• Number 76

TREND OF THE INCIDENCE AND MORTALITY RATE OF LIP CANCER IN CENTRAL SERBIA FROM 1999-2014

Aleksandra M. Ignjatović^1,2,
Miodrag M. Stojanović^1,2,
Zoran G. Milošević^1,2,
Marija R. Anđelković-Apostolović^1,2,
Branislava B. Stojković³,
Marija M. Topalović⁴,
Suzana A. Otašević^2,5

¹ University of Niš, Faculty of Medicine, Department of Medical Statistics and Informatics niš,serbija
²Public Health Institute Niš, niš,serbija
³ University of Niš, Faculty of Medicine, Department of Pediactric and Preventive Dentistry niš,serbija
⁴ University of Niš, Faculty of Medicine niš,serbija
⁵ University of Niš, Faculty of Medicine, Department of Microbiology and Immunology niš,serbija

...Abstract

Background: Lip cancer is the most frequent oral cancer.
The aim of this study was to present and estimate trends in the incidence and mortality of lip cancer in Central Serbia during a 16-year period, from 1999 to 2014.
Material and methods: This registry-based study was carried out based on the data extracted from publicly available Yearbooks of the Institute of Public Health of Serbia – Incidence and Mortality in Central Serbia, from 1999 to 2014. The trend and the annual percentage change (APC) of the incidence and mortality rate with the corresponding 95% confidence intervals were calculated by performing joinpoint regression analyses.
Results: A total number of 1,922 cases (1,402 in men and 520 in women) of lip cancer were registered in Central Serbia from 1999 to 2014. The crude rate (CR) and age-standardized rate (ASR-W) of the incidence in males decreased (p=0.001, p<0.001, respectively) during the study period with APC of 4.3%, 5.2%, respectively. In females, CR and ASR-W of incidence showed the only significant trend between 2003-2014, 2006-2014, respectively with APC 12.3, 24.3%, respectively. ASR-W of mortality rate in males showed the decreasing trend with APC 4.5%.
Conclusions: Our results reveal that the incidence of lip cancer declines trough the study period. The mortality rate is low and stable.

Key words:lip cancer, incidence rate, mortality rate, cancer registry, trends

...Authors and Reprint Information

Address of correspondence:
Lecturer Aleksandra Ignjatović, MD.PhD,
Faculty of Medicine,Department of Medical Statistics and Informatics,
81 Dr Zoran Đinđić Blvd, 18000 Niš, Serbia
E-mail:drsalea@yahoo.com