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ACTA
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Table of Contents for Decembar 2018 • Volume 34 • Number 78 |
APPLICATION OF CORTICOSTEROIDS IN DENTISTRY
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Marija G. Jovanović1,
1
UNIVERSITY OF NIŠ, FACULTY OF MEDICINE, PHD. STUDENT,
NIŠ, SERBIA |
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| ...Abstract |
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Introduction: Corticosteroids (CS)
are natural or synthetic hormones that affect nearly every aspect of
human physiology. In the clinical sense, by reducing the symptoms of
inflammation and immunosuppression, CS act symptomatically, decreasing
problems of the underlying disease or the current state of the patient.
According to application, corticosteroids are divided into topical,
local and systemic way of use. Topical use of CS makes vasoconstriction,
lowers mast cells degranulation, and reduces the permeability of
capillaries reducing the amounts of released histamine from basophils
and mast cells. The main goal of this therapy is to relieve or at least
reduce pain in patients, which has an impact on overall health,
nutrition, speech. Soft tissue inflammations that require the
application of CS are: recurrent aphthous stomatitis, oral submucosal
fibrosis, keloids and hypertrophic scars, mucocele; painful syndrome
with manifestations in the head and neck: Bechet syndrome, pemfigoid
syndrome, bullous pemfigoid,Oral Lichen planus, etc.; that reduces the
need for taking analgetics .In oral surgery they are used for the
treatment of the impacted wisdom teeth and other serious interventions
which apart from analgesics (NSAIDS and narcotic analgesics) require CS
in order to reduce trizmus, swelling and pain. There are numerous
studies that suggest the time and route of the administration CS in
lower impacted wisdom teeth surgery, as well as different combinations
of CS with other medications in order to reduce morbidity this such an
intervention. Local application of CS is indicated in this treatment of
gigantocellular lesions and can replace the surgical procedures.
Key words: corticosteroids, dentistry, inflammation
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