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ACTA
STOMATOLOGICA
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Table of Contents for
June 2021 • Volume 37 • Number 83

PHYSICAL AND MECHANICAL PROPERTIES OF THE CONVENTIONAL GLASS IONOMER CEMENT INCORPORATED WITH CATIONIC SUBSTANCES

Aleksandar G. Dimkov¹,
John W. Nicholson^2,3,
Elizabeta S. Gjorgievska¹

¹SS CYRIL AND METHODIUS UNIVERSITY, FACULTY OF DENTISTRY, DEPARTMENT FOR PEDIATRIC AND PREVENTIVE DENTISTRY, SKOPJE, REPUBLIC OF NORTH MACEDONIA
² BLUEFIELD CENTRE FOR BIOMATERIALS, LONDON, UNITED KINGDOM
³ QUEEN MARY UNIVERSITY OF LONDON, BARTS & THE LONDON SCHOOL OF MEDICINE AND DENTISTRY, DENTAL PHYSICAL SCIENCES, INSTITUTE OF DENTISTRY, LONDON, UNITED KINGDOM

...Abstract

Background: The effect of the antimicrobial agents benzalkonium chloride (BC) and cetylpyridinium chloride (CPC) on the restorative glass ionomer tooth cement (GIC) Fuji IX was investigated.
Aim of the study: The aim of the study was to determine whether the addition of antimicrobial compounds impairs the physical and mechanical properties of the commercial GIC Fuji IX.
Materials and Methods: The concentrations of 1%, 2% and 3% of antimicrobial agentsBC and CPC, by weight of the cement, were added during the mixing phase and different effects were studied.In most samples, there was a slight change in setting time. Samples with 4 mm diameter and 6 mm height were used to measure compressive strength and release. The release of antimicrobial compounds was analysed by UV-visible spectrophotometry at a wavelength of 259 nm for CPC and 214 nm for BC, in deionized water.
Results: The obtained results showed that the release takes place through the diffusion mechanism in the first 2-3 hours, and the diffusion coefficients vary depending on the concentration. The values range is from 1.97 x 10-14 -1.78 x 10-12 m2 s-1.Release of antimicrobial compound had ceased after seven days, with total release representing between 2.15 and 4.84% of the initial additive loading.
Conclusion: Both compounds have minor effect on the setting time of the GIC. The reduction of compressive strength is not statistically significant. CPC containing cements (1 and 2%), were statistically significantly weaker, than those containing BC (p<0.05).Both antimicrobial compounds have shown constant release from the GIC with values which are directly proportional both to the time and to the concentration.

Key words: benzalkonium chloride, cetylpyridium chloride, controlled release, diffusion, glass-ionomer

...Authors and Reprint Information

Address of correspondence:
Dr. Aleksandar Dimkov, DDM, PhD,
Faculty of Dental Medicine Department of Pediatric and Preventive
Dentistry Mother Theresa 17, 1000 Skoplje Macedonia
Email: dimkovaleksandar@gmail.com
Phone number +38970341 551