THE MULTIFACETED ROLE OF

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STOMATOLOGICA
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Table of Contents for
Decembar 2024 • Volume 40 • Number 90

THE MULTIFACETED ROLE OF HYALURONIC ACID IN DENTISTRY

Alessio Rosa¹,
Luca Testarelli²*,
Alberto Maria Pujia³,
Claudio Arcuri⁴,
Massimo Galli²,
Lorenzo Arcuri²

¹DEPARTMENT OF CHEMICAL SCIENCE AND TECHNOLOGIES, DENTISTRY, UNIVERSITY OF ROME TOR VERGATA, ROME, ITALY²DEPARTIMENT OF ODONTOSTOMATOLOGICAL AND MAXILLOFACIAL SCIENCES, SAPIENZA UNIVERSITY OF ROME, ROME, ITALY³DEPARTMENT OF BIOMEDICINE AND PREVENTION, UNIVERSITY OF ROME TOR VERGATA, ROME, ITALY⁴DEPARTMENT OF CLINICAL SCIENCES AND TRANSLATIONAL MEDICINE, UNIVERSITY OF ROME TOR VERGATA, ROME, ITALY

...Abstract

Background: Topical treatments are known to effectively deliver high doses of drugs directly to both the soft tissues of the gums and periodontal ligament, as well as to the hard structures like the alveolar bone and cementum. In addition to its well-established role in promoting healing post dental procedures, hyaluronic acid (HA) is now being recognized as a viable supportive therapy for chronic inflammatory conditions.
Materijal and Methods: Our study was conducted to systematically review the available literature on two fronts: the efficacy of HA as an adjunctive treatment for chronic inflammation and the benefits of HA in dental healing. We searched PubMed, Google Scholar, and Ovid using a combination of keywords and MeSH terms;
Results: from the 28 studies selected based on our inclusion criteria, which covered three papers related to gingivitis, thirteen to chronic periodontitis, seven to dental surgeries (including implants and sinus lifts), and three to oral ulcers.
Conclusions: we found that topical HA application not only significantly aids postoperative dental recovery but also bodes well among patients with chronic gingival/periodontal inflammation and those suffering from oral ulcers.

Key words: hyaluronic acid, oral health, biocompatible material

...Authors and Reprint Information

Address of correspondence:
Luca testarelli, DDM,
Sapienza University of Rome, Rome, Italy
E-mail: luca.testarelli@uniroma1.it